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Prescription Drugs

Participate in our Drug Study

For this study, we are looking for healthy adult participants between the ages of 21 and 35. Every volunteer will need to show up for three sessions, which will run between four to six hours each. Participants in these sessions will be given a placebo or a dosage of medicine (either baclofen or lorazepam).

About our study

Our research aims to comprehend how two drugs, baclofen and lorazepam, affect brain function.

Lorazepam is a member of the benzodiazepine medication family, which is often prescribed to treat seizures, insomnia, and anxiety disorders. It functions by increasing the brain's production of gamma-aminobutyric acid (GABA), a neurotransmitter that calms the nervous system.


Muscle spasticity, such as that observed in multiple sclerosis or spinal cord injury, is the main condition that is treated with the muscle relaxant and antispasmodic drug baclofen. It reduces muscular stiffness by stimulating GABA receptors within the spinal cord, which lessens the amount of information that is sent from the neurons to the muscles.

We want to shed insight on these drugs' potential therapeutic benefits beyond their established clinical usage by examining how transcranial magnetic stimulation (TMS) affects brain communication. Comprehending the pharmacological underpinnings of brain communication may pave the way for the creation of novel therapeutic interventions for a range of neurological disorders.

What to expect?

TMS and Menstrual cycle questionnaires before session 1

Drug intervention

Post-intervention measurements, MoCa assessment  and urine sample

Preliminary measurements, MoCA assessment

 1.5 hour break


Faith Adams, PhD Student

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